Magnesium Sulphate

Used in a number of situations in obstetrics:

  • prophylaxis in pre-eclampsia

  • treatment of eclamptic seizure

  • pre-term labour to promote fetal neuroprotection

       (NICE article)

Those women deemed at higher risk of eclamptic seizures will be loaded with 4g MgSO4 over 5-15mins, followed by 1g/hr for 24hrs.

In life-threatening situations where IV access is not possible, or is being attained, it can also be given IM mixed with 1ml 1% lignocaine.

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